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V.A. Recruits Millionth Veteran for Million Veteran Program Genetic Database

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V.A. Recruits Millionth Veteran for Million Veteran Program Genetic Database

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The millionth vet joined the database on the afternoon of Nov. 8. Staff who had waited a dozen years for this second wept.

Because the purpose approached, the division had began an intensive electronic mail marketing campaign, encouraging vets to enroll on-line or at V.A. medical facilities. Within the few weeks constructing as much as the millionth vet, what had been just a few hundred enrollees a day become hundreds. The division created a ticker, which it posted on-line, displaying the numbers.

“It is a present to the world,” mentioned Dr. Shereef Elnahal, the below secretary for well being within the Division sVeterans Affairs.

The V.A. will proceed to enroll extra vets to the database, however this was a symbolic second.

For years, researchers have been constructing giant databases for genetic analysis. Utilizing them they’ve discovered, for instance, genes that seem to confer resistance to dementia and ones that more than likely contribute to weight problems. The discoveries present paths to understanding these ailments and growing remedies.

There are different giant genetic databases, however they’ve principally been in-built Europe and embrace few minorities. The V.A. says its database provides a extra various inhabitants: 175,000 individuals with African ancestry and 80,000 Hispanics joined the Million Veteran Program. The database additionally consists of 100,000 ladies.

“It’s a large funding and scientific alternative,” mentioned Dr. Amit V. Khera, a genetic researcher at Massachusetts Common Hospital. He’s not a V.A. researcher, however he has used the information via collaborations with researchers who’re affiliated with the division.

Because the database acquired members, about 600 V.A. researchers registered to make use of it. The end result up to now has been greater than 350 papers on ailments and problems, together with post-traumatic stress dysfunction, coronary heart illness, hypertension and nonalcoholic liver illness.

For instance, mentioned Dr. Sumitra Muralidhar, director of the Million Veteran Program, researchers discovered genes linked to having flashbacks of traumatic occasions, a function of post-traumatic stress. Now, Dr. Muralidhar mentioned, investigators can examine these genes and the function they play, which can assist in growing remedies for PTSD.

The division additionally says it’s being aware of affected person privateness. Though researchers can look at genetic and different knowledge and hyperlinks to medical data, fewer than 10 individuals on the V.A. have the hyperlinks that tie data to people. These data, Dr. Muralidhar mentioned, are held at a facility in Boston that’s “closely secured.”

In 2019, a nurse at a V.A. hospital advised Octavia Harris, 60, of San Antonio, concerning the Million Veteran Program. She signed up and mentioned taking part was an opportunity to assist different vets and to assist herself.

Ms. Harris, who retired from the Navy in 2012 after 30 years of service, mentioned three circumstances run in her household — diabetes, hypertension and arthritis. She is hoping that along with her genetic and well being info added to that of so many others, researchers will make helpful discoveries.

In her household, Ms. Harris mentioned, individuals died younger.

“We haven’t lived past the age of 70,” she mentioned. “I need to go previous 70.”

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